Loss of desire, also known as low libido. Can affect women at certain times of life.
There are many obvious times such as during pregnancy, after having a baby, during menopause. However some women experience most of the time. 
Low libido can have a range of physical or psychological causes, including:
*Stress
*Depression
*Excessive drug use or alcohol.
*Medication side effects
*Hormone issues (drop in testosterone)
*Relationship issues
And many more reasons. If you are struggling with low libido it is worth visiting your GP in the first instance. They can assess for any physiological aspects. If ruled out sex therapy can help assist you in reconnecting with your sexuality and help with any relational issues.